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The reduction of GSH activity by ethacrynic acid (EA), an effective loop diuretic used in clinical practice [81], has also been shown to increase cell sensitivity to free radicals

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[PUBMED Abstract] Bartram J, Wade R, Vora A, et al.: Excellent outcome of minimal residual disease-defined low-risk patients is sustained with more than 10 years follow-up: results of UK paediatric acute lymphoblastic leukaemia trials 1997-2003

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